Dual DNA methylation patterns in the CNS reveal developmentally poised chromatin and monoallelic expression of critical genes.
As a first step towards discovery of genes expressed from only one allele in the CNS, we click here used a tiling array assay for DNA sequences that are both methylated and unmethylated (the MAUD assay).We analyzed regulatory regions of the entire mouse brain transcriptome, and found that approximately 10% of the genes assayed showed dual DNA methy